Inhibition of MYC by the SMARCB1 tumor suppressor

SMARCB1 encodes the SNF5 subunit of the SWI/SNF chromatin remodeler. SNF5 also interacts with the oncoprotein transcription factor MYC and is proposed to stimulate MYC activity. The concept that SNF5 is a coactivator for MYC, however, is at odds with its role as a tumor-suppressor, and with observat...

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Detalles Bibliográficos
Autores principales: Weissmiller, April M., Wang, Jing, Lorey, Shelly L., Howard, Gregory C., Martinez, Ernest, Liu, Qi, Tansey, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494882/
https://www.ncbi.nlm.nih.gov/pubmed/31043611
http://dx.doi.org/10.1038/s41467-019-10022-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494882/
https://www.ncbi.nlm.nih.gov/pubmed/31043611
http://dx.doi.org/10.1038/s41467-019-10022-5

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