A modular degron library for synthetic circuits in mammalian cells

Tight control over protein degradation is a fundamental requirement for cells to respond rapidly to various stimuli and adapt to a fluctuating environment. Here we develop a versatile, easy-to-handle library of destabilizing tags (degrons) for the precise regulation of protein expression profiles in...

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Detalles Bibliográficos
Autores principales: Chassin, Hélène, Müller, Marius, Tigges, Marcel, Scheller, Leo, Lang, Moritz, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494899/
https://www.ncbi.nlm.nih.gov/pubmed/31043592
http://dx.doi.org/10.1038/s41467-019-09974-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494899/
https://www.ncbi.nlm.nih.gov/pubmed/31043592
http://dx.doi.org/10.1038/s41467-019-09974-5

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