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Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved

Alzheimer's disease (AD) and Parkinson's disease (PD) are age-associated neurodegenerative disorders characterized by the misfolding and aggregation of alpha-synuclein (aSyn) and tau, respectively. The coexistence of aSyn and tau aggregates suggests a strong overlap between tauopathies and...

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Detalles Bibliográficos
Autores principales: Vasili, Eftychia, Dominguez-Meijide, Antonio, Outeiro, Tiago Fleming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494944/
https://www.ncbi.nlm.nih.gov/pubmed/31105524
http://dx.doi.org/10.3389/fnmol.2019.00107