Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

BACKGROUND: Lipoprotein(a) [Lp(a)], a major carrier of oxidized phospholipids (OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it remains unclear whether elevated Lp(a) and OxPL drive disease progression and are therefore targets for therapeutic intervention. OBJEC...

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Detalles Bibliográficos
Autores principales: Zheng, Kang H., Tsimikas, Sotirios, Pawade, Tania, Kroon, Jeffrey, Jenkins, William S.A., Doris, Mhairi K., White, Audrey C., Timmers, Nyanza K.L.M., Hjortnaes, Jesper, Rogers, Maximillian A., Aikawa, Elena, Arsenault, Benoit J., Witztum, Joseph L., Newby, David E., Koschinsky, Marlys L., Fayad, Zahi A., Stroes, Erik S.G., Boekholdt, S. Matthijs, Dweck, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494952/
https://www.ncbi.nlm.nih.gov/pubmed/31047003
http://dx.doi.org/10.1016/j.jacc.2019.01.070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494952/
https://www.ncbi.nlm.nih.gov/pubmed/31047003
http://dx.doi.org/10.1016/j.jacc.2019.01.070

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