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Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections
Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and quantification of fluorescent protein signals deep inside the tissues remained a challenge. Here, we developed vDISCO, a pressure driven, nanobody...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494982/ https://www.ncbi.nlm.nih.gov/pubmed/30598527 http://dx.doi.org/10.1038/s41593-018-0301-3 |