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Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and quantification of fluorescent protein signals deep inside the tissues remained a challenge. Here, we developed vDISCO, a pressure driven, nanobody...

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Detalles Bibliográficos
Autores principales: Cai, Ruiyao, Pan, Chenchen, Ghasemigharagoz, Alireza, Todorov, Mihail Ivilinov, Förstera, Benjamin, Zhao, Shan, Bhatia, Harsharan S., Parra-Damas, Arnaldo, Mrowka, Leander, Theodorou, Delphine, Rempfler, Markus, Xavier, Anna L.R., Kress, Benjamin T., Benakis, Corinne, Steinke, Hanno, Liebscher, Sabine, Bechmann, Ingo, Liesz, Arthur, Menze, Bjoern, Kerschensteiner, Martin, Nedergaard, Maiken, Ertürk, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494982/
https://www.ncbi.nlm.nih.gov/pubmed/30598527
http://dx.doi.org/10.1038/s41593-018-0301-3