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Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, their abnormality is associated with various brain...

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Detalles Bibliográficos
Autores principales: Ni, Peiyan, Noh, Haneul, Shao, Zhicheng, Zhu, Qian, Guan, Youxin, Park, Joshua J., Arif, Fatima, Park, James M., Abani, Chiderah, Beaudreault, Cameron, Park, Joy S., Berry, Elizabeth, Moghadam, Alexander, Stanton, Patric, Hutchinson, John N., Andrews, Bill, Faux, Clare, Parnevelas, John, Eisenberg, Leonard M., Park, Kyungjoon, Bolshakov, Vadim Y., Chung, Sangmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495066/
https://www.ncbi.nlm.nih.gov/pubmed/31061832
http://dx.doi.org/10.1016/j.omtm.2019.04.002