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Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis

MicroRNAs (miRNAs) act as regulators of aging at the tissue or organism level or as regulators of cellular senescence. Targeted deletion of miR-126 in mice causes partial embryonic lethality, but its biological function in the liver is still largely unknown. Here, we deleted miR-126a, using the CRIS...

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Detalles Bibliográficos
Autores principales:	Yan, Yi, Qin, Dan, Hu, Bian, Zhang, Chunjing, Liu, Shenghui, Wu, Dongde, Huang, Wendong, Huang, Xingxu, Wang, Liqiang, Chen, Xiangmei, Zhang, Lisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079/ https://www.ncbi.nlm.nih.gov/pubmed/31051334 http://dx.doi.org/10.1016/j.omtn.2019.04.002

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