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Enhanced Immunogenicity and Protective Efficacy of a Campylobacter jejuni Conjugate Vaccine Coadministered with Liposomes Containing Monophosphoryl Lipid A and QS-21

Campylobacter jejuni is among the most common causes of diarrheal disease worldwide and efforts to develop protective measures against the pathogen are ongoing. One of the few defined virulence factors targeted for vaccine development is the capsule polysaccharide (CPS). We have developed a capsule...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Amritha, Schumack, Nina M., Gariepy, Christina L., Eggleston, Heather, Nunez, Gladys, Espinoza, Nereyda, Nieto, Monica, Castillo, Rosa, Rojas, Jesus, McCoy, Andrea J., Beck, Zoltan, Matyas, Gary R., Alving, Carl R., Guerry, Patricia, Poly, Frédéric, Laird, Renee M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495334/
https://www.ncbi.nlm.nih.gov/pubmed/31043512
http://dx.doi.org/10.1128/mSphere.00101-19