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Meta-analysis of Plasmodium falciparum var Signatures Contributing to Severe Malaria in African Children and Indian Adults

The clinical presentation of severe Plasmodium falciparum malaria differs between children and adults, but the mechanistic basis for this remains unclear. Contributing factors to disease severity include total parasite biomass and the diverse cytoadhesive properties mediated by the polymorphic var g...

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Detalles Bibliográficos
Autores principales: Duffy, Fergal, Bernabeu, Maria, Babar, Prasad H., Kessler, Anne, Wang, Christian W., Vaz, Marina, Chery, Laura, Mandala, Wilson L., Rogerson, Stephen J., Taylor, Terrie E., Seydel, Karl B., Lavstsen, Thomas, Gomes, Edwin, Kim, Kami, Lusingu, John, Rathod, Pradipsinh K., Aitchison, John D., Smith, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495371/
https://www.ncbi.nlm.nih.gov/pubmed/31040236
http://dx.doi.org/10.1128/mBio.00217-19