Binding of Staphylococcus aureus Protein A to von Willebrand Factor Is Regulated by Mechanical Force

Binding of Staphylococcus aureus to the large plasma glycoprotein von Willebrand factor (vWF) is controlled by hydrodynamic flow conditions. Currently, we know little about the molecular details of this shear-stress-dependent interaction. Using single-molecule atomic force microscopy, we demonstrate...

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Detalles Bibliográficos
Autores principales: Viela, Felipe, Prystopiuk, Valeria, Leprince, Audrey, Mahillon, Jacques, Speziale, Pietro, Pietrocola, Giampiero, Dufrêne, Yves F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495375/
https://www.ncbi.nlm.nih.gov/pubmed/31040240
http://dx.doi.org/10.1128/mBio.00555-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495375/
https://www.ncbi.nlm.nih.gov/pubmed/31040240
http://dx.doi.org/10.1128/mBio.00555-19

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