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Astrocyte D-serine modulates the activation of neuronal NOS leading to the development of mechanical allodynia in peripheral neuropathy

Spinal D-serine plays an important role in nociception via an increase in phosphorylation of the N-Methyl-D-aspartate (NMDA) receptor GluN1 subunit (pGluN1). However, the cellular mechanisms underlying this process have not been elucidated. Here, we investigate the possible role of neuronal nitric o...

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Detalles Bibliográficos
Autores principales: Choi, Sheu-Ran, Roh, Dae-Hyun, Yoon, Seo-Yeon, Choi, Hoon-Seong, Kang, Suk-Yun, Han, Ho-Jae, Beitz, Alvin James, Lee, Jang-Hern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495448/
https://www.ncbi.nlm.nih.gov/pubmed/30900515
http://dx.doi.org/10.1177/1744806919843046