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Melatonin protects mesenchymal stem cells from autophagy‐mediated death under ischaemic ER‐stress conditions by increasing prion protein expression

OBJECT: The purpose of this study was to explore whether melatonin could protect mesenchymal stem cells (MSCs) against ischaemic injury, by inhibiting endoplasmic reticulum (ER) stress and autophagy both in vivo and in vitro. MATERIALS AND METHODS: To confirm the protective effect of melatonin again...

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Detalles Bibliográficos
Autores principales: Lee, Jun Hee, Yoon, Yeo Min, Han, Yong‐Seok, Jung, Seo Kyung, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495509/
https://www.ncbi.nlm.nih.gov/pubmed/30430685
http://dx.doi.org/10.1111/cpr.12545