Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer’s disease

BACKGROUND: Discrepant and often contradictory results have accumulated regarding the antidepressant and pro-cognitive effects of serotonin transporter (SERT) antagonists in Alzheimer’s disease. METHODS: To address the discrepancy, we measured the activity and density of SERT in the neocortex of 3–2...

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Detalles Bibliográficos
Autores principales: Metaxas, Athanasios, Anzalone, Marco, Vaitheeswaran, Ramanan, Petersen, Sussanne, Landau, Anne M., Finsen, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495598/
https://www.ncbi.nlm.nih.gov/pubmed/31043179
http://dx.doi.org/10.1186/s13195-019-0491-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495598/
https://www.ncbi.nlm.nih.gov/pubmed/31043179
http://dx.doi.org/10.1186/s13195-019-0491-2

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