Population Pharmacokinetic Analyses for Plazomicin Using Pooled Data from Phase 1, 2, and 3 Clinical Studies

Plazomicin is an aminoglycoside with activity against multidrug-resistant Enterobacteriaceae. Plazomicin is dosed on a milligram-per-kilogram-of-body-weight basis and administered by a 30-min intravenous infusion every 24 h, with dose adjustments being made for renal impairment and a body weight (BW...

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Detalles Bibliográficos
Autores principales: Trang, Michael, Seroogy, Julie D., Van Wart, Scott A., Bhavnani, Sujata M., Kim, Aryun, Gibbons, Jacqueline A., Ambrose, Paul G., Rubino, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496156/
https://www.ncbi.nlm.nih.gov/pubmed/30670433
http://dx.doi.org/10.1128/AAC.02329-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496156/
https://www.ncbi.nlm.nih.gov/pubmed/30670433
http://dx.doi.org/10.1128/AAC.02329-18

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