A FASII Inhibitor Prevents Staphylococcal Evasion of Daptomycin by Inhibiting Phospholipid Decoy Production

Daptomycin is a treatment of last resort for serious infections caused by drug-resistant Gram-positive pathogens, such as methicillin-resistant Staphylococcus aureus. We have shown recently that S. aureus can evade daptomycin by releasing phospholipid decoys that sequester and inactivate the antibio...

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Detalles Bibliográficos
Autores principales: Pee, Carmen J. E., Pader, Vera, Ledger, Elizabeth V. K., Edwards, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496159/
https://www.ncbi.nlm.nih.gov/pubmed/30718253
http://dx.doi.org/10.1128/AAC.02105-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496159/
https://www.ncbi.nlm.nih.gov/pubmed/30718253
http://dx.doi.org/10.1128/AAC.02105-18

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