The Nedd8‐activating enzyme inhibitor MLN4924 (TAK‐924/Pevonedistat) induces apoptosis via c‐Myc‐Noxa axis in head and neck squamous cell carcinoma

OBJECTIVES: The present study aimed to reveal expression status of the neddylation enzymes in HNSCC and to elucidate the anticancer efficacy and the underlying mechanisms of inhibiting neddylation pathway. MATERIALS AND METHODS: The expression levels of neddylation enzymes were estimated by Western...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjuan, Liang, Yupei, Li, Lihui, Wang, Xiaofang, Yan, Zi, Dong, Changsheng, Zeng, Mu‐Sheng, Zhong, Qian, Liu, Xue‐Kui, Yu, Jinha, Sun, Shuyang, Liu, Xiaojun, Kang, Jihui, Zhao, Hu, Jeong, Lak Shin, Zhang, Yanmei, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496207/
https://www.ncbi.nlm.nih.gov/pubmed/30341788
http://dx.doi.org/10.1111/cpr.12536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496207/
https://www.ncbi.nlm.nih.gov/pubmed/30341788
http://dx.doi.org/10.1111/cpr.12536

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