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Preconditioning of umbilical cord‐derived mesenchymal stem cells by rapamycin increases cell migration and ameliorates liver ischaemia/reperfusion injury in mice via the CXCR4/CXCL12 axis

OBJECTIVES: Transfusion of umbilical cord‐derived mesenchymal stem cells (UC‐MSCs) is a novel strategy for treatment of various liver diseases. However, the therapeutic effect of UC‐MSCs is limited because only a few UC‐MSCs migrate towards the damaged regions. In this study, we observed the effects...

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Detalles Bibliográficos
Autores principales: Zheng, Jun, Li, Hui, He, Liying, Huang, Yiming, Cai, Jianye, Chen, Liang, Zhou, Chaorong, Fu, Hongyuan, Lu, Tongyu, Zhang, Yingcai, Yao, Jia, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496237/
https://www.ncbi.nlm.nih.gov/pubmed/30537044
http://dx.doi.org/10.1111/cpr.12546