Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel

OBJECTIVES: The aim of this study was to elucidate the antimitotic mechanism of zerumbone and to investigate its effect on the HeLa cells in combination with other mitotic blockers. MATERIALS AND METHODS: HeLa cells and fluorescence microscopy were used to analyse the effect of zerumbone on cancer c...

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Detalles Bibliográficos
Autores principales: Ashraf, Shabeeba M., Sebastian, Jomon, Rathinasamy, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496756/
https://www.ncbi.nlm.nih.gov/pubmed/30525278
http://dx.doi.org/10.1111/cpr.12558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496756/
https://www.ncbi.nlm.nih.gov/pubmed/30525278
http://dx.doi.org/10.1111/cpr.12558

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