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The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis
Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper cardiogenesis. The canonical Wnt/β-catenin inhibitor Dkk1 has been shown to be sufficient to trigger cardiogenesis in gain-of-function experiments performed in multiple model...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496975/ https://www.ncbi.nlm.nih.gov/pubmed/30797757 http://dx.doi.org/10.1016/j.ydbio.2019.02.009 |