The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper cardiogenesis. The canonical Wnt/β-catenin inhibitor Dkk1 has been shown to be sufficient to trigger cardiogenesis in gain-of-function experiments performed in multiple model...

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Detalles Bibliográficos
Autores principales: Guo, Yanchun, Dorn, Tatjana, Kühl, Susanne J., Linnemann, Alexander, Rothe, Melanie, Pfister, Astrid S., Vainio, Seppo, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Kühl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496975/
https://www.ncbi.nlm.nih.gov/pubmed/30797757
http://dx.doi.org/10.1016/j.ydbio.2019.02.009

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