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Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer
OBJECTIVE: The present study aimed to investigate the expression of Numb in ovarian cancer tissues and to assess the effect of Numb on cell proliferation, invasion, and EMT in ovarian cancer. METHODS: Real-time PCR and Western blotting were used to detect the mRNA and protein expression of Numb, PAK...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497004/ https://www.ncbi.nlm.nih.gov/pubmed/31114254 http://dx.doi.org/10.2147/OTT.S194725 |