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Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer

OBJECTIVE: The present study aimed to investigate the expression of Numb in ovarian cancer tissues and to assess the effect of Numb on cell proliferation, invasion, and EMT in ovarian cancer. METHODS: Real-time PCR and Western blotting were used to detect the mRNA and protein expression of Numb, PAK...

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Detalles Bibliográficos
Autores principales: Liang, Jiabin, Han, Bingbing, Zhang, Yunhe, Yue, Qingfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497004/
https://www.ncbi.nlm.nih.gov/pubmed/31114254
http://dx.doi.org/10.2147/OTT.S194725