Female-biased embryonic death from genomic instability-induced inflammation

Genomic instability (GIN) can trigger cellular responses including checkpoint activation, senescence, and inflammation (1,2). Though extensively studied in cell culture and cancer paradigms, little is known about the impact of GIN during embryonic development, a period of rapid cellular proliferatio...

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Detalles Bibliográficos
Autores principales: McNairn, Adrian J., Chuang, Chen-Hua, Bloom, Jordana C., Wallace, Marsha D., Schimenti, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497049/
https://www.ncbi.nlm.nih.gov/pubmed/30787433
http://dx.doi.org/10.1038/s41586-019-0936-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497049/
https://www.ncbi.nlm.nih.gov/pubmed/30787433
http://dx.doi.org/10.1038/s41586-019-0936-6

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