Cargando…

Development of a Cx46 Targeting Strategy for Cancer Stem Cells

Gap-junction-mediated cell-cell communication enables tumor cells to synchronize complex processes. We previously found that glioblastoma cancer stem cells (CSCs) express higher levels of the gap junction protein Cx46 compared to non-stem tumor cells (non-CSCs) and that this was necessary and suffic...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulkearns-Hubert, Erin E., Torre-Healy, Luke A., Silver, Daniel J., Eurich, Jennifer T., Bayik, Defne, Serbinowski, Emily, Hitomi, Masahiro, Zhou, John, Przychodzen, Bartlomiej, Zhang, Renliang, Sprowls, Samuel A., Hale, James S., Alban, Tyler J., Berezovsky, Artem, Bell, Brent A., Lockman, Paul R., Jha, Babal K., Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497083/
https://www.ncbi.nlm.nih.gov/pubmed/31018124
http://dx.doi.org/10.1016/j.celrep.2019.03.079