The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death

Reactive oxygen species (ROS) play a key role in development of heart failure but, at a cellular level, their effects range from cytoprotection to induction of cell death. Understanding how this is regulated is crucial to develop novel strategies to ameliorate only the detrimental effects. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Meijles, Daniel N., Zoumpoulidou, Georgia, Markou, Thomais, Rostron, Kerry A., Patel, Rishi, Lay, Kenneth, Handa, Balvinder S., Wong, Bethany, Sugden, Peter H., Clerk, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497135/
https://www.ncbi.nlm.nih.gov/pubmed/30771309
http://dx.doi.org/10.1016/j.yjmcc.2019.02.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497135/
https://www.ncbi.nlm.nih.gov/pubmed/30771309
http://dx.doi.org/10.1016/j.yjmcc.2019.02.006

Ejemplares similares