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High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach

Lifelong infection of the gastric mucosa by Helicobacter pylori can lead to peptic ulcers and gastric cancer. However, how the bacteria maintain chronic colonization in the face of constant mucus and epithelial cell turnover in the stomach is unclear. Here, we present a new model of how H. pylori es...

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Detalles Bibliográficos
Autores principales: Fung, Connie, Tan, Shumin, Nakajima, Mifuyu, Skoog, Emma C., Camarillo-Guerrero, Luis Fernando, Klein, Jessica A., Lawley, Trevor D., Solnick, Jay V., Fukami, Tadashi, Amieva, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497225/
https://www.ncbi.nlm.nih.gov/pubmed/31048876
http://dx.doi.org/10.1371/journal.pbio.3000231