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High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach
Lifelong infection of the gastric mucosa by Helicobacter pylori can lead to peptic ulcers and gastric cancer. However, how the bacteria maintain chronic colonization in the face of constant mucus and epithelial cell turnover in the stomach is unclear. Here, we present a new model of how H. pylori es...
Autores principales: | Fung, Connie, Tan, Shumin, Nakajima, Mifuyu, Skoog, Emma C., Camarillo-Guerrero, Luis Fernando, Klein, Jessica A., Lawley, Trevor D., Solnick, Jay V., Fukami, Tadashi, Amieva, Manuel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497225/ https://www.ncbi.nlm.nih.gov/pubmed/31048876 http://dx.doi.org/10.1371/journal.pbio.3000231 |
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