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High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

Pore-forming proteins (PFPs) represent a functionally important protein family, that are found in organisms from viruses to humans. As a major branch of PFPs, bacteria pore-forming toxins (PFTs) permeabilize membranes and usually cause the death of target cells. E. coli hemolysin ClyA is the first m...

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Detalles Bibliográficos
Autores principales: Peng, Wei, de Souza Santos, Marcela, Li, Yang, Tomchick, Diana R., Orth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497250/
https://www.ncbi.nlm.nih.gov/pubmed/31048915
http://dx.doi.org/10.1371/journal.pone.0213423