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Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system

Enterococcus faecalis is an opportunistic pathogen with an intrinsically high resistance to lysozyme, a key effector of the innate immune system. This high level of resistance requires a complex network of transcriptional regulators and several genes (oatA, pgdA, dltA and sigV) acting synergisticall...

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Detalles Bibliográficos
Autores principales: Smith, Robert E., Salamaga, Bartłomiej, Szkuta, Piotr, Hajdamowicz, Natalia, Prajsnar, Tomasz K., Bulmer, Gregory S., Fontaine, Thierry, Kołodziejczyk, Justyna, Herry, Jean-Marie, Hounslow, Andrea M., Williamson, Mike P., Serror, Pascale, Mesnage, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497286/
https://www.ncbi.nlm.nih.gov/pubmed/31048927
http://dx.doi.org/10.1371/journal.ppat.1007730