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How does a protein’s structure spell the difference between health and disease? Our journey to understand glaucoma-associated myocilin

Over 20 years ago, alterations to the protein myocilin were confirmed to be linked to a heritable form of the prevalent eye disease, glaucoma, and 10 years ago, my lab set out to develop a deeper understanding of myocilin in its normal and diseased state. We have made strides in understanding how ge...

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Detalles Bibliográficos
Autor principal: Lieberman, Raquel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497288/
https://www.ncbi.nlm.nih.gov/pubmed/31009450
http://dx.doi.org/10.1371/journal.pbio.3000237