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A benchmark-driven approach to reconstruct metabolic networks for studying cancer metabolism
Genome-scale metabolic modeling has emerged as a promising way to study the metabolic alterations underlying cancer by identifying novel drug targets and biomarkers. To date, several computational methods have been developed to integrate high-throughput data with existing human metabolic reconstruct...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497301/ https://www.ncbi.nlm.nih.gov/pubmed/31009458 http://dx.doi.org/10.1371/journal.pcbi.1006936 |