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BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data
Genome-scale metabolic models (GEMs) are mathematically structured knowledge bases of metabolism that provide phenotypic predictions from genomic information. GEM-guided predictions of growth phenotypes rely on the accurate definition of a biomass objective function (BOF) that is designed to include...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497307/ https://www.ncbi.nlm.nih.gov/pubmed/31009451 http://dx.doi.org/10.1371/journal.pcbi.1006971 |