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ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

BACKGROUND: Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment. Herein, we analyze the effect of ARHGAP18 on the regulation of EC alignment and...

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Detalles Bibliográficos
Autores principales: Lay, Angelina J., Coleman, Paul R., Formaz‐Preston, Ann, Ting, Ka Ka, Roediger, Ben, Weninger, Wolfgang, Schwartz, Martin A., Vadas, Mathew A., Gamble, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497359/
https://www.ncbi.nlm.nih.gov/pubmed/30630384
http://dx.doi.org/10.1161/JAHA.118.010057