Cargando…
ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis
BACKGROUND: Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment. Herein, we analyze the effect of ARHGAP18 on the regulation of EC alignment and...
Autores principales: | Lay, Angelina J., Coleman, Paul R., Formaz‐Preston, Ann, Ting, Ka Ka, Roediger, Ben, Weninger, Wolfgang, Schwartz, Martin A., Vadas, Mathew A., Gamble, Jennifer R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497359/ https://www.ncbi.nlm.nih.gov/pubmed/30630384 http://dx.doi.org/10.1161/JAHA.118.010057 |
Ejemplares similares
-
YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment
por: Coleman, Paul R., et al.
Publicado: (2020) -
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells
por: Lovelace, Michael D., et al.
Publicado: (2017) -
Caveolae control the anti-inflammatory phenotype of senescent endothelial cells
por: Powter, Elizabeth E, et al.
Publicado: (2015) -
The aging endothelium
por: Ting, Ka Ka, et al.
Publicado: (2021) -
The Tumour Vasculature as a Target to Modulate Leucocyte Trafficking
por: Zhao, Yang, et al.
Publicado: (2021)