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Detection of post-vaccination enhanced dengue virus infection in macaques: An improved model for early assessment of dengue vaccines

The need for improved dengue vaccines remains since the only licensed vaccine, Dengvaxia, shows variable efficacy depending on the infecting dengue virus (DENV) type, and increases the risk of hospitalization for severe dengue in children not exposed to DENV before vaccination. Here, we developed a...

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Detalles Bibliográficos
Autores principales: Borges, Maria Beatriz, Marchevsky, Renato Sergio, Carvalho Pereira, Renata, da Silva Mendes, Ygara, Almeida Mendes, Luiz Gustavo, Diniz-Mendes, Leonardo, Cruz, Michael A., Tahmaoui, Ouafaâ, Baudart, Sébastien, Freire, Marcos, Homma, Akira, Schneider-Ohrum, Kirsten, Vaughn, David W., Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Caride, Elena, Warter, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497418/
https://www.ncbi.nlm.nih.gov/pubmed/31009499
http://dx.doi.org/10.1371/journal.ppat.1007721