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MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting MAT2A and MAT2B genes

Hepatocellular carcinoma (HCC) is characterized by the down-regulation of the liver-specific methyladenosyltransferase 1A (MAT1A) gene, encoding the S-adenosylmethionine synthesizing isozymes MATI/III, and the up-regulation of the widely expressed methyladenosyltransferase 2A (MAT2A), encoding MATII...

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Detalles Bibliográficos
Autores principales: Simile, Maria M., Peitta, Graziella, Tomasi, Maria L., Brozzetti, Stefania, Feo, Claudio F., Porcu, Alberto, Cigliano, Antonio, Calvisi, Diego F., Feo, Francesco, Pascale, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497462/
https://www.ncbi.nlm.nih.gov/pubmed/31073374
http://dx.doi.org/10.18632/oncotarget.26838