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Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection

Purpose: The epithelial to mesenchymal transition (EMT) is pivotal for driving metastasis and recurrence in lung cancer. Some in vitro reports have shown that statins suppress EMT by inactivating mutant p53 functions. Several clinical trials of conventional treatments with statins have been performe...

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Detalles Bibliográficos
Autores principales: Nishikawa, Shigeto, Menju, Toshi, Takahashi, Koji, Miyata, Ryo, Chen-Yoshikawa, Toyofumi Fengshi, Sonobe, Makoto, Yoshizawa, Akihiko, Sabe, Hisataka, Sato, Tosiya, Date, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497483/
https://www.ncbi.nlm.nih.gov/pubmed/31114376
http://dx.doi.org/10.2147/CMAR.S200819