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Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection
Purpose: The epithelial to mesenchymal transition (EMT) is pivotal for driving metastasis and recurrence in lung cancer. Some in vitro reports have shown that statins suppress EMT by inactivating mutant p53 functions. Several clinical trials of conventional treatments with statins have been performe...
Autores principales: | Nishikawa, Shigeto, Menju, Toshi, Takahashi, Koji, Miyata, Ryo, Chen-Yoshikawa, Toyofumi Fengshi, Sonobe, Makoto, Yoshizawa, Akihiko, Sabe, Hisataka, Sato, Tosiya, Date, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497483/ https://www.ncbi.nlm.nih.gov/pubmed/31114376 http://dx.doi.org/10.2147/CMAR.S200819 |
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