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Nicotinic alpha‐7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non‐alcoholic steatohepatitis

AIMS/INTRODUCTION: Non‐alcoholic steatohepatitis (NASH), which occurs in association with insulin resistance and hepatic fat accumulation, is characterized by chronic liver injury and fibrosis. NASH onset and progression is closely related to hepatic inflammation, which is partly regulated by the va...

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Detalles Bibliográficos
Autores principales: Kimura, Kumi, Inaba, Yuka, Watanabe, Hitoshi, Matsukawa, Toshiya, Matsumoto, Michihiro, Inoue, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497582/
https://www.ncbi.nlm.nih.gov/pubmed/30369082
http://dx.doi.org/10.1111/jdi.12964