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Early administration of dapagliflozin preserves pancreatic β‐cell mass through a legacy effect in a mouse model of type 2 diabetes

AIMS/INTRODUCTION: The preservation of pancreatic β‐cell mass is an essential factor in the onset and development of type 2 diabetes mellitus. Recently, sodium–glucose cotransporter 2 inhibitors have been launched as antihyperglycemic agents, and their organ‐protective effects are attracting attenti...

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Detalles Bibliográficos
Autores principales: Kanno, Ayumi, Asahara, Shun‐ichiro, Kawamura, Mao, Furubayashi, Ayuko, Tsuchiya, Shoko, Suzuki, Emi, Takai, Tomoko, Koyanagi‐Kimura, Maki, Matsuda, Tomokazu, Okada, Yuko, Ogawa, Wataru, Kido, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497604/
https://www.ncbi.nlm.nih.gov/pubmed/30290061
http://dx.doi.org/10.1111/jdi.12945