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Conformational Change of Amyloid-β 40 in Association with Binding to GM1-Glycan Cluster
Aggregates of amyloid-β (Aβ) peptide are well known to be the causative substance of Alzheimer’s disease (AD). Recent studies showed that monosialotetrahexosylganglioside (GM1) clusters induce the pathological aggregation of Aβ peptide responsible for the onset and development of AD. However, the ef...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497634/ https://www.ncbi.nlm.nih.gov/pubmed/31048748 http://dx.doi.org/10.1038/s41598-019-43117-6 |