Computational prediction and in vitro validation of VEGFR1 as a novel protein target for 2,3,7,8-tetrachlorodibenzo-p-dioxin

The toxic manifestations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental contaminant, primarily depend on its ability to activate aryl hydrocarbon receptor (AhR), which is a ligand-dependent transcription factor belonging to the superfamily of basic-helix-loop-helix DNA-binding prote...

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Detalles Bibliográficos
Autores principales: Chitrala, Kumaraswamy Naidu, Yang, Xiaoming, Busbee, Brandon, Singh, Narendra P., Bonati, Laura, Xing, Yongna, Nagarkatti, Prakash, Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497656/
https://www.ncbi.nlm.nih.gov/pubmed/31048752
http://dx.doi.org/10.1038/s41598-019-43232-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497656/
https://www.ncbi.nlm.nih.gov/pubmed/31048752
http://dx.doi.org/10.1038/s41598-019-43232-4

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