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Structural basis for functional interactions in dimers of SLC26 transporters

The SLC26 family of transporters maintains anion equilibria in all kingdoms of life. The family shares a 7 + 7 transmembrane segments inverted repeat architecture with the SLC4 and SLC23 families, but holds a regulatory STAS domain in addition. While the only experimental SLC26 structure is monomeri...

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Detalles Bibliográficos
Autores principales: Chang, Yung-Ning, Jaumann, Eva A., Reichel, Katrin, Hartmann, Julia, Oliver, Dominik, Hummer, Gerhard, Joseph, Benesh, Geertsma, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497670/
https://www.ncbi.nlm.nih.gov/pubmed/31048734
http://dx.doi.org/10.1038/s41467-019-10001-w