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Acidic Stress Triggers Sodium-Coupled Bicarbonate Transport and Promotes Survival in A375 Human Melanoma Cells

Melanoma cells preserve intracellular pH (pH(i)) within a viable range despite an acidic ambient pH that typically falls below pH 7.0. The molecular mechanisms underlying this form of acidic preservation in melanoma remain poorly understood. Previous studies had demonstrated that proton transporters...

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Detalles Bibliográficos
Autores principales: Yang, Oscar C. Y., Loh, Shih-Hurng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497716/
https://www.ncbi.nlm.nih.gov/pubmed/31048755
http://dx.doi.org/10.1038/s41598-019-43262-y