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Acidic Stress Triggers Sodium-Coupled Bicarbonate Transport and Promotes Survival in A375 Human Melanoma Cells
Melanoma cells preserve intracellular pH (pH(i)) within a viable range despite an acidic ambient pH that typically falls below pH 7.0. The molecular mechanisms underlying this form of acidic preservation in melanoma remain poorly understood. Previous studies had demonstrated that proton transporters...
Autores principales: | Yang, Oscar C. Y., Loh, Shih-Hurng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497716/ https://www.ncbi.nlm.nih.gov/pubmed/31048755 http://dx.doi.org/10.1038/s41598-019-43262-y |
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