In silico structural elucidation of RNA-dependent RNA polymerase towards the identification of potential Crimean-Congo Hemorrhagic Fever Virus inhibitors

The Crimean-Congo Hemorrhagic Fever virus (CCHFV) is a segmented negative single-stranded RNA virus (−ssRNA) which causes severe hemorrhagic fever in humans with a mortality rate of ~50%. To date, no vaccine has been approved. Treatment is limited to supportive care with few investigational drugs in...

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Detalles Bibliográficos
Autores principales: Mirza, Muhammad Usman, Vanmeert, Michiel, Froeyen, Matheus, Ali, Amjad, Rafique, Shazia, Idrees, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497722/
https://www.ncbi.nlm.nih.gov/pubmed/31048746
http://dx.doi.org/10.1038/s41598-019-43129-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497722/
https://www.ncbi.nlm.nih.gov/pubmed/31048746
http://dx.doi.org/10.1038/s41598-019-43129-2

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