Cargando…

Blood–brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals

To test whether genetic variants in PICALM, BIN1, CD2AP, and RIN3—suggested to be involved in blood–brain barrier amyloid-β transcytosis pathways—associate with Alzheimer’s disease, all dementia, suggested vascular dementia, and stroke, and whether such associations are independent of the strong ε4...

Descripción completa

Detalles Bibliográficos
Autores principales: Juul Rasmussen, Ida, Tybjærg-Hansen, Anne, Rasmussen, Katrine Laura, Nordestgaard, Børge G., Frikke-Schmidt, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497814/
https://www.ncbi.nlm.nih.gov/pubmed/30830563
http://dx.doi.org/10.1007/s10654-019-00498-2