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Pim-1 inhibitor SMI-4a suppresses tumor growth in non-small cell lung cancer via PI3K/AKT/mTOR pathway

Background: In the present study, we aimed to investigate the effect of proviral integration site for moloney murine leukemia virus-1 (Pim-1) inhibitor (SMI-4a) on the progression of non-small cell lung cancer (NSCLC). Materials and methods: The effects of SMI-4a on proliferation, apoptosis, and cel...

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Detalles Bibliográficos
Autores principales: Jiang, Wenjie, Chen, Yuan, Song, Xing, Shao, Yingjie, Ning, Zhonghua, Gu, Wendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497832/
https://www.ncbi.nlm.nih.gov/pubmed/31114247
http://dx.doi.org/10.2147/OTT.S203142