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Mapping the spectrum of 3D communities in human chromosome conformation capture data

Several experiments show that the three dimensional (3D) organization of chromosomes affects genetic processes such as transcription and gene regulation. To better understand this connection, researchers developed the Hi-C method that is able to detect the pairwise physical contacts of all chromosom...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hoon, Kim, Yeonghoon, Lee, Sungmin, Durang, Xavier, Stenberg, Per, Jeon, Jae-Hyung, Lizana, Ludvig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497878/
https://www.ncbi.nlm.nih.gov/pubmed/31048738
http://dx.doi.org/10.1038/s41598-019-42212-y