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Lack of Brain Serotonin Affects Feeding and Differentiation of Newborn Cells in the Adult Hypothalamus

Serotonin (5-HT) is a crucial signal in the neurogenic niche microenvironment. Dysregulation of the 5-HT system leads to mood disorders but also to changes in appetite and metabolic rate. Tryptophan hydroxylase 2-deficient (Tph2(-/-)) mice depleted of brain 5-HT display alterations in these paramete...

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Detalles Bibliográficos
Autores principales: van Lingen, Marike, Sidorova, Maria, Alenina, Natalia, Klempin, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498036/
https://www.ncbi.nlm.nih.gov/pubmed/31106202
http://dx.doi.org/10.3389/fcell.2019.00065