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Marked improvement in leptomeningeal carcinomatosis and spinal cord metastases following alectinib treatment of crizotinib-resistant, ALK-positive lung adenocarcinoma

We report a case of 50-year-old Japanese female with anaplastic lymphoma kinase (ALK)-positive, crizotinib-resistant lung adenocarcinoma, whose leptomeningeal carcinomatosis and spinal cord metastases were dramatically improved by the second-generation ALK inhibitor alectinib. Magnetic resonance ima...

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Detalles Bibliográficos
Autores principales: Kuribayashi, Hidehiko, Abe, Shinji, Kuse, Naoyuki, Kusunoki, Yuji, Narato, Ritsuko, Saito, Hitoshi, Gemma, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498346/
https://www.ncbi.nlm.nih.gov/pubmed/31149429
http://dx.doi.org/10.1007/s13691-015-0231-9